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Preheat oven to 450 degrees F. Spray a baking sheet with cooking spray and set aside.
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Mix the garlic powder, melted butter, hot sauce and salt and pepper in a small bowl.
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Place the cauliflower florets into a large bowl. Pour the hot sauce mixture. Using two serving spoons, stir the cauliflower so each floret is completely coated in sauce. (You could also place the cauliflower into a Ziploc bag and pour in the sauce – shake to coat).
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Spread the coated cauliflower florets onto the prepared baking sheet. Bake for 20 minutes.
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Serve with your favorite dip (ranch, blue cheese, etc. )